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Related trials

SPIRIT IV, 2010 - everolimus eluting stent vs paclitaxel eluting stent

BASKET-PROVE (SES), 2010 - sirolimus eluting stent vs bare-metal stent

GISSOC II, 2010 - sirolimus eluting stent vs bare-metal stent

SORT-OUT-3, 2010 - zotarolimus eluting stent vs sirolimus eluting stent

RESOLUTE, 2010 - zotarolimus eluting stent vs everolimus eluting stent

BASKET-PROVE (EES), 2010 - everolimus eluting stent vs bare-metal stent

TRIANA, 2009 - primary ballon angioplasty vs tenecteplase

DEBATER (SES vs BMS), 2009 - sirolimus eluting stent vs bare-metal stent

ISAR TEST 2 (vs SES), 2009 - dual sirolimus, probucol eluting stent vs sirolimus eluting stent

ZEST (vs PES), 2009 - zotarolimus eluting stent vs paclitaxel eluting stent

ISAR-LEFT-MAIN, 2009 - sirolimus eluting stent vs paclitaxel eluting stent

NORDISTEMI, 2009 - thrombolysis + angioplasty vs immediate thrombolysis

ISAR TEST 3 (BP), 2009 - sirolimus biodegradable polymer vs sirolimus eluting stent

COMPARE, 2009 - everolimus eluting stent vs paclitaxel eluting stent

ENDEAVOR IV, 2009 - zotarolimus eluting stent vs paclitaxel eluting stent

Juwana, 2009 - sirolimus eluting stent vs paclitaxel eluting stent

GENIUS-STEMI, 2009 - Genous stent vs bare-metal stent

ZEST AMI (vs PES), 2009 - zotarolimus eluting stent vs paclitaxel eluting stent

ISAR-TEST-4 (biodegradable polymer), 2009 - sirolimus biodegradable polymer vs sirolimus eluting stent

ZEST (vs SES), 2009 - zotarolimus eluting stent vs sirolimus eluting stent

PASEO, 2009 - drug-eluting stents vs bare-metal stent

ISAR TEST 3 (PF), 2009 - polymer free sirolimus stent vs sirolimus eluting stent

ISAR TEST 2 (vs ZES), 2009 - dual sirolimus, probucol eluting stent vs zotarolimus eluting stent

Thiele, 2009 - sirolimus ES vs MIDCAB

ZEST AMI (vs SES), 2009 - zotarolimus eluting stent vs sirolimus eluting stent



See also:

  • All coronary artery disease clinical trials
  • All acute myocardial infarction clinical trials
  • All clinical trials of PCI
  • All clinical trials of drug-eluting stents
    		•  

    PASEO study, 2009

    Facebook    pdf : drug-eluting stents - myocardial revascularization for acute myocardial infarction

    Treatments

    Studied treatment paclitaxel-eluting stents and sirolimus-eluting stents
    Control treatment bare metal stent
    Concomittant treatment aspirin, clopidogrel 300 mg, unfractionated heparin 70 U/kg, upstream glycoprotein IIb/IIIa inhibitor.
    Remarks 3 arms : SES, PES, BM

    Patients

    Patients patients with ST-elevation myocardial infarction within 12 hours from symptom onset
    Exclusion criteria active internal bleeding or bleeding disorder within the last month; history of intracranial hemorrhage, intracranial neoplasm, arteriovenous malformation, or aneurysm; allergy to one of the study medications; history of stroke within the last month; history of surgical procedure or trauma within the last month; aortic dissection; fibrinolytic therapy within the previous 24 hours; thrombocytopenia; hemorrhagic retinopathy; currently taking warfarin; pregnancy
    Baseline characteristics
    age 62 y 
    diabetes (%) 26% 
    Female (%) 29% 
    STEMI 100% 

    Method and design

    Randomized effectives 180 / 90 (studied vs. control)
    Design Parallel groups
    Blinding open
    Follow-up duration 4.3 years
    Lost to follow-up 0%
    Primary endpoint TLR 1 year


    Results

    No results available for this trial - no clinical endpoint reported

    Meta-analysis of all similar trials:

    Drug eluting stent in coronary artery disease for all type of patients

    Drug eluting stent in coronary artery disease for acute myocardial infarction

    myocardial revascularization in acute myocardial infarction for all type of patients

    PCI in acute myocardial infarction for all type of patients



    Reference(s)

    Trials register # NA
    • Di Lorenzo E, De Luca G, Sauro R, Varricchio A, Capasso M, Lanzillo T, Manganelli F, Mariello C, Siano F, Pagliuca MR, Stanco G, Rosato G. The PASEO (PaclitAxel or Sirolimus-Eluting Stent Versus Bare Metal Stent in Primary Angioplasty) Randomized Trial.. JACC Cardiovasc Interv 2009 Jun;2:515-23
      Pubmed | Hubmed | Fulltext
    • Di Lorenzo E, Sauro R, Varricchio A, Carbone G, Cortese G, Capasso M, Lanzillo T, Manganelli F, Mariello C, Siano F, Pagliuca MR, Stanco G, Rosato G, De Luca G. Long-Term outcome of drug-eluting stents compared with bare metal stents in ST-segment elevation myocardial infarction: results of the paclitaxel- or sirolimus-eluting stent versus bare metal stent in Primary Angioplasty (PASEO) Randomized Trial.. Circulation 2009;120:964-72
      Pubmed | Hubmed | Fulltext

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