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Systematic review and meta-analysis

This trial is included in the following systematic reviews and meta-analyses:

acute myocardial infarction - myocardial revascularization - all type of patients

acute myocardial infarction - PCI - all type of patients


Related trials

TRIANA, 2009 - primary ballon angioplasty vs tenecteplase

DEBATER (SES vs BMS), 2009 - sirolimus eluting stent vs bare-metal stent

NORDISTEMI, 2009 - thrombolysis + angioplasty vs immediate thrombolysis

Juwana, 2009 - sirolimus eluting stent vs paclitaxel eluting stent

ZEST AMI (vs PES), 2009 - zotarolimus eluting stent vs paclitaxel eluting stent

PASEO, 2009 - drug-eluting stents vs bare-metal stent

ZEST AMI (vs SES), 2009 - zotarolimus eluting stent vs sirolimus eluting stent

CARESS, 2008 - thrombolysis + angioplasty vs immediate thrombolysis

HORIZONS-AMI Stent, 2008 - paclitaxel eluting stent vs bare-metal stent

MISSION, 2008 - sirolimus eluting stent vs bare-metal stent

DEDICATION, 2008 - drug-eluting stents vs bare-metal stent

Díaz de la Llera, 2007 - sirolimus eluting stent vs bare-metal stent

SESAMI, 2007 - sirolimus eluting stent vs bare-metal stent

PROSIT, 2006 - sirolimus eluting stent vs paclitaxel eluting stent

HAAMU-STENT, 2006 - paclitaxel eluting stent vs bare-metal stent

PASSION, 2006 - paclitaxel eluting stent vs bare-metal stent

WEST, 2006 - systematic PCI (+stent) vs no systematic PCI

TYPHOON, 2006 - sirolimus eluting stent vs bare-metal stent

ZWOLLE 6, 2005 - primary stenting vs balloon angioplasty

CAPITAL AMI, 2005 - systematic PCI (+stent) vs no systematic PCI

senior PAMI, 2005 - primary PCI vs Thrombolysis

CAPITAL AMI, 2005 - thrombolysis + angioplasty vs immediate thrombolysis

Di Lorenzo et al., 2005 - sirolimus eluting stent vs paclitaxel eluting stent

GRACIA-1, 2004 - systematic PCI (+stent) vs no systematic PCI

MERLIN (Sutton), 2004 - immediate systematic ballon angioplastyte vs no immediate angioplasty



See also:

  • All acute myocardial infarction clinical trials
  • All clinical trials of PCI
  • All clinical trials of thrombolysis + angioplasty
    		•  

    NORDISTEMI study, 2009

    [NCT00161005] Facebook    pdf : thrombolysis + angioplasty - myocardial revascularization for acute myocardial infarction

    Treatments

    Studied treatment transfer for immediate coronary angiography and intervention
    Control treatment concervative strategy
    ischemia-guided treatment in local hospitals with transfer for rescue PCI if needed
    Concomittant treatment optimal medical therapy (tenecteplase, aspirin 300 mg, enoxaparin 30 mg iv 1mg/kg sc, clopidogrel 300 mg

    Patients

    Patients patients with STEMI of less than 6 hours of duration and more than 90 minutes expected time delay to PCI

    Method and design

    Randomized effectives 134 / 132 (studied vs. control)
    Design Parallel groups
    Blinding open
    Follow-up duration 1y
    Geographic area Norway
    Primary endpoint death, reMI, stroke, new ischaemia


    Results

    Endpoint Studied treat.
    n/N     Control treat.
    n/N     Graph RR [95% CI]

    death, reinfarctus, stroke

    NA / 134
         NA / 132
         0,36 [0,16;0,81]     0 2 1.0

    Relative risks
    Endpoint Events (%) Relative Risk 95% CI Endpoint definition
    in the trial    		 Ref
    Studied treat. Control treat.
    The primary endpoint (if exists) appears in blod characters
    Reference(s) used for data extraction:

    Endpoint studied treat. control treat. mean diff

    Absolute risk reduction
    Endpoint Events rate Absolute risk
    reduction (ARR)
    Studied treat. Control treat.

    Meta-analysis of all similar trials:

    myocardial revascularization in acute myocardial infarction for all type of patients

    PCI in acute myocardial infarction for all type of patients



    Reference(s)

    Trials register # NCT00161005

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