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Systematic review and meta-analysis

This trial is included in the following systematic reviews and meta-analyses:

percutaneous coronary intervention - anticoagulant - all type of patients

percutaneous coronary intervention - antithrombotics - all type of patients


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See also:

  • All percutaneous coronary intervention clinical trials
  • All clinical trials of antithrombotics
  • All clinical trials of Enoxaparin
  •  

    Galeote study, 2001

    download pdf: Enoxaparin | antithrombotics for percutaneous coronary intervention

    Treatments

    Studied treatment Enoxaparin 0.75 mg/kg bolus
    Control treatment UFH 70 U/kg bolus, then titrated to ACT > 200
    Concomittant treatment Abciximab

    Patients

    Patients PTCA patients with stable/unstable angina or AMI

    Method and design

    Randomized effectives 50 / 49 (studied vs. control)


    Results

    Endpoint Studied treat.
    n/N
    Control treat.
    n/N
    Graph RR [95% CI]

    Bleeding

    1 / 50
    4 / 49
    classic 0,25 [0,03;2,12]

    MACE

    5 / 50
    3 / 49
    classic 1,63 [0,41;6,47]
    0 2 1.0

    Relative risks
    Endpoint Events (%) Relative Risk 95% CI Endpoint definition
    in the trial
    Ref
    Studied treat. Control treat.
    Bleeding 1 / 50 (2,0%) 4 / 49 (8,2%) 0,25 [0,03;2,12]
    MACE 5 / 50 (10,0%) 3 / 49 (6,1%) 1,63 [0,41;6,47]
    The primary endpoint (if exists) appears in blod characters
    Reference(s) used for data extraction:

    Endpoint studied treat. control treat. mean diff

    Absolute risk reduction
    Endpoint Events rate Absolute risk
    reduction (ARR)
    Studied treat. Control treat.
    Bleeding 2,00% 8,16% -61,6‰
    MACE 10,00% 6,12% 3,9%

    Meta-analysis of all similar trials:

    anticoagulant in percutaneous coronary intervention for all type of patients

    antithrombotics in percutaneous coronary intervention for all type of patients



    Reference(s)

    Trials register # NA
    • Galeote G, Hussein M, Sobrino N, Calvo L, Yunda H, Sa´nchez-. Combination abciximab and enoxaparin or unfractionated heparin during percutaneous coronary intervention: a randomised study. Eur Heart J 2001;22(Suppl):663
      Pubmed | Hubmed | Fulltext

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