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See also:

  • All venous thrombosis clinical trials

    Kearon study, 2004


    Studied treatment continuation for 2 additionnal months of warfarin adjusted to achieve a target INR between 2.0 and 3.0.
    Control treatment discontinuation (after 1 months)


    Inclusion criteria first episode of idiopathic venous thromboembolism; DVT demonstrated by bilateral compression ultrasonography of the proximal leg veins, and (if possible) bilateral impedance plethysmography; PE by ventilation-perfusion lung scan;
    Exclusion criteria other indications for, or contraindication to, long-termanticoagulant therapy; need for long-term treatment with nonsteroidal anti-inflammatory drugs, ticlopidine, sulfinpyrazone, dipyridamole, or more than 160 mg of aspirin per day; familial bleeding disorder; major psychiatric disorder; pregnant or could become pregnant
    Baseline characteristics
    time of randomization 1 months 

    Method and design

    Randomized effectives NA / NA (studied vs. control)
    Design Parallel groups
    Blinding double blind
    Follow-up duration 11 months (after randomizatio)
    Number of centre 13
    Geographic area Canada, US
    Primary endpoint recurrent VTE


    No results available for this trial - no clinical endpoint reported


    Trials register # NA
    • Kearon C, Ginsberg JS, Anderson DR, Kovacs MJ, Wells P, Julian JA, Mackinnon B, Demers C, Douketis J, Turpie AG, Van Nguyen P, Green D, Kassis J, Kahn SR, Solymoss S, Desjardins L, Geerts W, Johnston M, Weitz JI, Hirsh J, Gent M. Comparison of 1 month with 3 months of anticoagulation for a first episode of venous thromboembolism associated with a transient risk factor.. J Thromb Haemost 2004;2:743-9
      Pubmed | Hubmed | Fulltext

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