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See also:
All atrial fibrillation clinical trials
All clinical trials of new anticoagulants
All clinical trials of dabigatran
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Treatments
Studied treatment |
Dabigatran 110, 220, 300 mg twice daily
|
Control treatment |
warfarin
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Patients
Patients |
patients with non-valvular atrial fibrillation (paroxysmal, persistent or permanent) |
Inclusion criteria |
1) Hypertension; 2) Diabetes mellitus; 3) Left-side heart failure; 4) A previous ischemic stroke or transient ischemic attack; 5) Age 75 years or older; 6) history of coronary artery diseases; |
Method and design
Randomized effectives |
NA / NA (studied vs. control) |
Design |
Parallel groups |
Blinding |
open |
Geographic area |
Japan |
Primary endpoint |
major bleeding event, , |
Studied endpoints |
Incidence of major bleeding event, Incidence of clinically relevant bleeding event, Incidence of nuisance bleeding event, A composite clinical endpoint including the incidence of ischemic or haemorrhagic stroke (fatal or non-fatal), transient ischemic attacks, systemic embolism, myocardial infarction (fatal or non-fatal), other major adverse cardiac events, and death, The incidence of ischemic or haemorrhagic stroke (fatal or non-fatal), The incidence of transient ischemic attack, The incidence of systemic embolism, The incidence of myocardial infarction (fatal or non-fatal), The incidence of other major adverse cardiac events, The incidence of death, |
Results
No results available for this trial
- unpublished or not fully published trial
Meta-analysis of all similar trials:
antithrombotics in atrial fibrillation for primary prevention of thromboembolic events
new anticoagulants in atrial fibrillation for all type of patients
Reference(s)
unpublished (or not yet fully published) trial
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