Related trials
APPRAISE-1 (10mg od), 2009 - apixaban vs placebo
SEPIA-ACS1 TIMI 42, 2009 - otamixaban vs unfractioned heparin
PLATO, 2009 - ticagrelor + aspirin vs clopidogrel + aspirin
ATLAS ACS-TIMI 46, 2009 - rivaroxaban vs placebo
APPRAISE-1 (2.5 mg bid), 2009 - apixaban vs placebo
DISPERSE-2 (90mg), 2007 - ticagrelor + aspirin vs clopidogrel + aspirin
INTERACT, 2006 - enoxaparin vs UFH (on top of aspirin)
OASIS 5, 2006 - fondaparinux vs enoxaparin
PROTECT-TIMI 30, 2006 - Bivalirudin vs eptifibatide + heparin
SYNERGY, 2005 - enoxaparin vs UFH (on top of aspirin)
EVET, 2005 - enoxaparin vs tinzaparin
LoWASA, 2004 - warfarin vs control (on top of aspirin)
PENTUA, 2004 - fondaparinux vs enoxaparin
Zibaeenezhad, 2004 - warfarin vs control (on top of aspirin)
APRICOT-2, 2002 - warfarin vs control (on top of aspirin)
ASPECT-2 (coumadin+asp vs asp), 2002 - coumadin vs control (on top of aspirin)
WARIS, 2002 - warfarin vs control (on top of aspirin)
ASPECT-2 (coumadin vs aspirin), 2002 - coumadin vs aspirin
CHAMP, 2002 - warfarin vs control (on top of aspirin)
OASIS-2 Warfarin Substudy, 2001 - warfarin vs control (on top of aspirin)
CURE, 2001 - clopidogrel + aspirin vs aspirin
Huyhn, 2001 - warfarin vs placebo (on top of aspirin)
TIM, 2000 - triflusal vs aspirine
HIT-4, 1999 - Hirudin vs heparin
Klootwijk, 1999 - Efegatran vs heparin
See also:
All acute coronary syndrome clinical trials
All clinical trials of antithrombotics
All clinical trials of aspirin
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VA-pilot study, 0
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unpublished (or not yet fully published) trial
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Treatments
| Studied treatment |
Aspirin 324 mg/d
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| Control treatment |
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Patients
Method and design
| Randomized effectives |
26 / 24 (studied vs. control) |
| Follow-up duration |
3m |
Results
Endpoint
Studied treat. n/N
Control treat. n/N
Graph
RR [95% CI]
Non fatal MI
0 / 26
1 / 24
classic
0,18 [0,00;13,05]
Vascular death
1 / 26
3 / 24
classic
0,31 [0,03;2,76]
Non vascular death
0 / 26
0 / 24
classic
0,92 [0,00;229,49]
Non fatal stroke
0 / 26
0 / 24
classic
0,92 [0,00;229,49]
Vascular events
1 / 26
4 / 24
0,23 [0,03;1,92]
Major bleeding
0 / 26
0 / 24
classic
0,92 [0,00;229,49]
0
2
1.0
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Relative risks
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| Endpoint |
Events (%) |
Relative Risk |
95% CI |
Endpoint definition in the trial |
Ref |
| Studied treat. |
Control treat. |
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Non fatal MI
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0 / 26 (1,9%) |
1 / 24 (4,2%) |
0,46 |
[0,02;13,14] |
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Vascular death
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1 / 26 (3,8%) |
3 / 24 (12,5%) |
0,31 |
[0,03;2,76] |
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Non vascular death
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0 / 26 (1,9%) |
0 / 24 (2,1%) |
0,92 |
[0,02;44,72] |
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Non fatal stroke
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0 / 26 (1,9%) |
0 / 24 (2,1%) |
0,92 |
[0,02;44,72] |
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Vascular events
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1 / 26 (3,8%) |
4 / 24 (16,7%) |
0,23 |
[0,03;1,92] |
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Major bleeding
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0 / 26 (1,9%) |
0 / 24 (2,1%) |
0,92 |
[0,02;44,72] |
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The primary endpoint (if exists) appears in blod characters
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Reference(s) used for data extraction:
0:
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| Endpoint |
studied treat. |
control treat. |
mean diff |
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Absolute risk reduction
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| Endpoint |
Events rate |
Absolute risk reduction (ARR) |
| Studied treat. |
Control treat. |
| Vascular death |
3,85% |
12,50% |
-86,5‰
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| Vascular events |
3,85% |
16,67% |
-128,2‰
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Reference(s)
unpublished (or not yet fully published) trial
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