Related trials
APPRAISE-1 (10mg od), 2009 - apixaban vs placebo
SEPIA-ACS1 TIMI 42, 2009 - otamixaban vs unfractioned heparin
PLATO, 2009 - ticagrelor + aspirin vs clopidogrel + aspirin
ATLAS ACS-TIMI 46, 2009 - rivaroxaban vs placebo
APPRAISE-1 (2.5 mg bid), 2009 - apixaban vs placebo
DISPERSE-2 (90mg), 2007 - ticagrelor + aspirin vs clopidogrel + aspirin
INTERACT, 2006 - enoxaparin vs UFH (on top of aspirin)
OASIS 5, 2006 - fondaparinux vs enoxaparin
PROTECT-TIMI 30, 2006 - Bivalirudin vs eptifibatide + heparin
SYNERGY, 2005 - enoxaparin vs UFH (on top of aspirin)
EVET, 2005 - enoxaparin vs tinzaparin
LoWASA, 2004 - warfarin vs control (on top of aspirin)
PENTUA, 2004 - fondaparinux vs enoxaparin
Zibaeenezhad, 2004 - warfarin vs control (on top of aspirin)
APRICOT-2, 2002 - warfarin vs control (on top of aspirin)
ASPECT-2 (coumadin+asp vs asp), 2002 - coumadin vs control (on top of aspirin)
WARIS, 2002 - warfarin vs control (on top of aspirin)
ASPECT-2 (coumadin vs aspirin), 2002 - coumadin vs aspirin
CHAMP, 2002 - warfarin vs control (on top of aspirin)
OASIS-2 Warfarin Substudy, 2001 - warfarin vs control (on top of aspirin)
CURE, 2001 - clopidogrel + aspirin vs aspirin
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See also:
All acute coronary syndrome clinical trials
All clinical trials of direct factor Xa inhibitors
All clinical trials of apixaban
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APPRAISE 2 (CV185-068) study,
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[NCT00831441]
Ongoing trial
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Treatments
| Studied treatment |
apixaban 5mg twice daily
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| Control treatment |
placebo
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Patients
| Patients |
patients with a recent acute coronary syndrome |
| Inclusion criteria |
acute coronary syndrome; clinically stable; receiving standard of care for ACS
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| Exclusion criteria |
severe hypertension;
active bleeding or high risk for major bleeding; hemoglobin < 9 g/dL
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Method and design
| Randomized effectives |
10848 |
| Design |
Parallel groups |
| Blinding |
double blind |
| Primary endpoint |
Cv death, MI, ischemic stroke |
Results
No results available for this trial
- no clinical endpoint reported
Reference(s)
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