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04/03/2010 - RE-LY 150mg subgroup  -  dabigatran 150mg daily versus warfarin

  atrial fibrillation - antithrombotics - secondary prevention of thromboembolic events

04/02/2010 - BATTLESCARRED  -  drug treatment directed by plasma NTproBNP for 2 years versus usual care

  heart failure - BNP-guided management - all type of patients

29/01/2010 - BBS  -  off-pump CABG versus on-pump CABG

  CABG surgery - off-pump CABG - all type of patients

29/01/2010 - ThermoCool AF  -  catheter ablation versus antiarrhythmic drug therapy with a class I or III drug

  atrial fibrillation - catheter ablation - all type of patients

10/01/2010 - COMPARE  -  polymer based, everolimus-eluting stent (Xience V) versus polymer-based, paclitaxel-eluting stent (Taxus Liberte)

  stable angina - myocardial revascularization - all type of patient

  coronary artery disease - revascularization with drug eluting stent - all type of patients

  coronary artery disease - revascularization with drug eluting stent - unparticular patients

08/01/2010 - SALTIRE  -  atorvastatin 80mg daily versus placebo

  cardiovascular prevention - cholesterol lowering intervention - patient with related disease

  aortic stenosis - cholesterol lowering intervention - all type of patients

08/01/2010 - ASTRONOMER  -  rosuvastatin 40 mg daily versus placebo

  cardiovascular prevention - cholesterol lowering intervention - patient with related disease

  aortic stenosis - cholesterol lowering intervention - all type of patients

05/01/2010 - VTACH  -  catheter ablation for ventricular tachycardia (VT) plus implantable cardioverter defibrillator versus implantable cardioverter defibrillator alone

  ventricular tachycardia in patients with structural heart disease - catheter ablation of ventricular tachycardia - all type of patients

  patients with implantable cardioverter defibrillators - catheter ablation - all type of patients

26/12/2009 - ESSENTIAL (I and II)  -  enoximone titrated to 50 mg three times daily versus placebo

  heart failure - phosphodiesterase III inhibitors - all type of patients

22/12/2009 - ZEST AMI (vs PES)  -  zotarolimus-eluting stent (Endeavor) versus paclitaxel-eluting stent (Taxus Liberté)

  acute myocardial infarction - myocardial revascularization - all type of patients

  acute myocardial infarction - PCI - all type of patients

  coronary artery disease - myocardial revascularization - all type of patient

  coronary artery disease - revascularization with drug eluting stent - all type of patients

  coronary artery disease - revascularization with drug eluting stent - acute myocardial infarction

22/12/2009 - ZEST AMI (vs SES)  -  zotarolimus-eluting stent (Endeavor) versus sirolimus-eluting stents (Cypher)

  acute myocardial infarction - myocardial revascularization - all type of patients

  acute myocardial infarction - PCI - all type of patients

  coronary artery disease - myocardial revascularization - all type of patient

  coronary artery disease - revascularization with drug eluting stent - acute myocardial infarction

21/12/2009 - NAPLES (Tavano)  -  bivalirudin monotherapy versus unfractionated heparin plus tirofiban

  percutaneous coronary intervention - antithrombotics - all type of patients

  percutaneous coronary intervention - anticoagulant - all type of patients

16/12/2009 - DORADO  -  darusentan 50 mg, 100 mg or 300 mg versus placebo

  hypertension - anti hypertensive agent - patients with treatment-resistant hypertension

15/12/2009 - INSTEAD  -  thoracic endovascular repair (TEVAR) with a stent graft plus optimal medical therapy versus optimum medical management

  throracic aortic aneuvrism - endovascular treatment - all type of patients

12/12/2009 - PROTECT  -  natriuretic-peptide-guided therapy versus standard management

  heart failure - BNP-guided management - all type of patients

12/12/2009 - Troughton  -  BNP-guided treatment versus empirical trial-based therapy dictated by clinical acumen61Ø7Ow

  heart failure - BNP-guided management - all type of patients

11/12/2009 - RE-COVER  -  dabigatran 150 mg twice daily in a fixed-dose versus warfarin dose-adjusted to an INR between 2.0 and 3.0

  venous thrombosis - antithrombotics - all type of patients

  venous thrombosis - direct antithrombins - all type of patients

10/12/2009 - EINSTEIN-extension  -  rivaroxaban 20 mg once-daily for an additional 6 or 12 months versus placebo

  venous thrombosis - direct factor Xa inhibitors - all type of patients

01/12/2009 - ROOBY  -  off-pump CABG versus on-pump CABG

  CABG surgery - off-pump CABG - all type of patients

26/11/2009 - HeartMate II  -  continuous-flow HeartMate II ventricular assist device versus pulsatile-flow HeartMate XVE ventricular assist device

  heart failure - percutaneous left ventricular assist devices - all type of patients

21/11/2009 - REDEEM  -  dabigatran 4 dosages (50mg twice daily, 75mg twice daily, 110mg twice daily, 150mg twice daily) versus placebo

  post myocardial infarction - antithrombotics - all type of patients

  post acute coronary syndromes - antithrombotics - all type of patients

21/11/2009 - FAIR-HF  -  ferric carboxymaltose versus placebo

  heart failure - increasing hemoglobin concentration - all type of patients

15/11/2009 - CHAMPION-PLATFORM  -  cangrelor up front (cangrelor during PCI followed by 600 mg of clopidogrel) versus delayed clopidogrel (placebo during PCI followed by 600 mg of clopidogrel)

  percutaneous coronary intervention - antithrombotics - all type of patients

15/11/2009 - CHAMPION-PCI  -  cangrelor up front (cangrelor administered before percutaneous coronary intervention and followed by clopidogrel) versus clopidogrel up front (clopidogrel followed by placebo)

  percutaneous coronary intervention - antithrombotics - all type of patients

  percutaneous coronary intervention - pre treatment for PCI - stable and unstable ACS

28/10/2009 - BLOSSOM  -  lorcaserin 10 mg twice daily versus placebo

  obesity and overweight - All mecanism - all type of patients

26/10/2009 - Astrup (NN8022-1807 )  -  4 liraglutide doses (1.2 mg, 1.8 mg, 2.4 mg, or 3.0 mg daily) versus placebo

  obesity and overweight - All mecanism - all type of patients

16/10/2009 - OVER  -  endovascular repair versus open repair

  abdominal aortic aneurysm - endovascular treatment - all type of patients

11/10/2009 - IRIS  -  prophylactic ICD implantation early after myocardial infarction versus optimal medical therapy alone

  acute myocardial infarction - ICD - all type of patients

27/09/2009 - Nordic-Baltic Bifurcation Study III  -  Kissing balloon dilatation post-stenting of the main artery (one-stent technique) versus no kissing balloon dilatation

  coronary artery disease - revascularization with drug eluting stent - bifurcation lesion

27/09/2009 - DEBATER (SES vs BMS)  -  sirolimus-eluting stents versus bare-metal stents

  acute myocardial infarction - PCI - all type of patients

  coronary artery disease - revascularization with drug eluting stent - all type of patients

  coronary artery disease - revascularization with drug eluting stent - acute myocardial infarction

23/09/2009 - ENDEAVOR IV  -  zotarolimus-eluting stent (Endeavor) versus paclitaxel-eluting stent (Taxus)

  stable angina - myocardial revascularization - all type of patient

  coronary artery disease - myocardial revascularization - all type of patient

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