CACTUS , 2009 double stenting with SES versus single stenting

Circulation 2009;119:71-8  

double stenting with SES versus single stenting in patients with true coronary bifurcation lesions




Studied treatment elective
Control treatment stenting of only the main branch, with provisional side-branch T-stenting
Age (y) 66
male (%) 78.3



Patients patients with true coronary bifurcation lesions
Group sizes 177 / 173
diabetes 22.9%
hypertension 75.1
previous MI (%) 40%
prior PCI (%) 28.9
prior CABG (%) 5.1
LVEF (%) 56



Blindness open Inclusion period
Follow-up duration 6 months Centers 12
Lost to FU geographical localisation Europe
Primary endpoint cardiac death, myocardial infarction, or target-vessel revascularization Design Parallel groups



EndpointX1N1X0N0TE95% CI stent thrombosis - 173 - 177 1,47[0,25; 8,66] TLR - 173 - 177 1,16[0,53; 2,52] death - 173 - 177 0,33[0,01; 9,30] MI - 173 - 177 1,24[0,65; 2,36]0,22,01,0


Colombo A, Bramucci E, SaccĂ  S, Violini R, Lettieri C, Zanini R, Sheiban I, Paloscia L, Grube E, Schofer J, Bolognese L, Orlandi M, Niccoli G, Latib A, Airoldi F Randomized study of the crush technique versus provisional side-branch stenting in true coronary bifurcations: the CACTUS (Coronary Bifurcations: Application of the Crushing Technique Using Sirolimus-Eluting Stents) Study. Circulation 2009;119:71-8     [PMID: 19103990]   link to pdf  

 




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