hypertension - antiplatelets drug - all type of patients clinical trials results meta-analysis

<h1> <a href="TM7-2-antiplatelets drug-hypertension" > <strong>hypertension</strong> - antiplatelets drug </a> - all type of patients trial results systematic overview and meta-analysis </h1> <h2>Main characteristics of the included studies</h2> <table> <tr> <th>Trial</th> <th>Treatments</th> <th>Patients</th> <th>Methods</th> </tr> <tr> <td> <a href="../TRC_t4260.htm"> HOT, 1998 </a> <br> </td> <td> aspirin 75 mg daily<br>  <i>versus</i> <br> placebo </td> <td> patients aged 50-80 with hypertension and diastolic blood pressure between 100 mmHG and 115 mmHG </td> <td> follow-up mean 3.8 y (range 3.3-4.9y)<br> n=9399/9391<br> Factorial plan<br> Double blind <br> Europe, North and South America, and Asia </td> </tr> </table> <h2>References</h2> <p> <b>HOT, 1998 : </b> Hansson L, Zanchetti A, Carruthers SG, Dahlof B, Elmfeldt D, Julius S, Menard J, Rahn KH, Wedel H, Westerling SEffects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group. <i>Lancet 1998 Jun 13;351:1755-62</i> [PMID 9635947] </p> <p> <b>HOT, 1998 : </b> Hansson L, Zanchetti AThe Hypertension Optimal Treatment (HOT) Study--patient characteristics: randomization, risk profiles, and early blood pressure results. <i>Blood Press 1994;3:322-7</i> [PMID 7866597] </p>