coronary artery disease - revascularization with drug eluting stent - total occlusion clinical trials results meta-analysis

<h1> <a href="TM29-79-revascularization with drug eluting stent-coronary artery disease" > <strong>coronary artery disease</strong> - revascularization with drug eluting stent </a> - total occlusion trial results systematic overview and meta-analysis </h1> <h2>Main characteristics of the included studies</h2> <table> <tr> <th>Trial</th> <th>Treatments</th> <th>Patients</th> <th>Methods</th> </tr> <tr> <td> <a href="../TRC_t6571.htm"> PRISON II, 2006 </a> <br> NCT00258596 </td> <td> Cypher<br>  <i>versus</i> <br> BxVelocity </td> <td> Chronic total occlusion, positive exercise stress test </td> <td> follow-up 6 months<br> n=100/100<br> Parallel groups<br> single-blind <br> Belgium </td> </tr> <tr> <td> <a href="../TRC_t10839.htm"> SCANDSTENT (subgroup), 2006 </a> <br> </td> <td> SES implanted after successful recanalization<br>  <i>versus</i> <br> BMS implanted after successful recanalization </td> <td> patients with coronary artery disease and a total coronary occlusion > or = 15 mm in length </td> <td> follow-up 17 mo (angiography 7 mo)<br> n=64/63<br> Parallel groups<br> open <br> </td> </tr> <tr> <td> <a href="../TRC_t6637.htm"> GISSOC II, 0 </a> <br> NCT00220558 </td> <td> Cypher Select-TM Sirolimus Eluting Stent<br>  <i>versus</i> <br> SONIC-TM Bare Metal Stent </td> <td> Chronic Total Occlusion lesions </td> <td> follow-up <br> n=-9/-9<br> <br> <br> </td> </tr> <tr> <td> <a href="../TRC_t6665.htm"> PRISON III, 2007 </a> <br> NCT00428454 </td> <td> Endeavor<br>  <i>versus</i> <br> Cypher </td> <td> patients with total coronary occlusions for at least 2 weeks with evidence of ischemia related to the occluded coronary artery </td> <td> follow-up 8 months<br> n=-9/-9<br> Parallel groups<br> open <br> </td> </tr> </table> <h2>References</h2> <p> <b>PRISON II, 2006 : </b> Suttorp MJ, Laarman GJ, Rahel BM, Kelder JC, Bosschaert MA, Kiemeneij F, Ten Berg JM, Bal ET, Rensing BJ, Eefting FD, Mast EGPrimary Stenting of Totally Occluded Native Coronary Arteries II (PRISON II): a randomized comparison of bare metal stent implantation with sirolimus-eluting stent implantation for the treatment of total coronary occlusions. <i>Circulation 2006;114:921-8</i> [PMID 16908768] </p> <p> <b>PRISON III, 2007 : </b> Suttorp MJ, Laarman GJA randomized comparison of sirolimus-eluting stent implantation with zotarolimus-eluting stent implantation for the treatment of total coronary occlusions: rationale and design of the PRImary Stenting of Occluded Native coronary arteries III (PRISON III) study. <i>Am Heart J 2007 Sep;154:432-5</i> [PMID 17719285] </p> <p> <b>SCANDSTENT (subgroup), 2006 : </b> Kelbaek H, Helqvist S, Thuesen L, Kløvgaard L, Jørgensen E, Saunamäki K, Krusell LR, Bøtker HE, Engstrøm T, Jensen GVSirolimus versus bare metal stent implantation in patients with total coronary occlusions: subgroup analysis of the Stenting Coronary Arteries in Non-Stress/Benestent Disease (SCANDSTENT) trial. <i>Am Heart J 2006;152:882-6</i> [PMID 17070149] 10.1016/j.ahj.2006.03.028 </p>